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|Tested species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant fragment corresponding to a region within amino acids 1 and 334 of Human MEK6|
|Purification||Antigen affinity chromatography|
|Storage buffer||0.1M tris glycine, pH 7, with 10% glycerol|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
|Immunohistochemistry (Paraffin) (IHC (P))||1:100-1:1000|
|Western Blot (WB)||1:500-1:3000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
PA5-28572 targets MEK6 in IF, IHC (P), and WB applications and shows reactivity with Human samples.
The PA5-28572 immunogen is recombinant fragment corresponding to a region within amino acids 1 and 334 of Human MEK6.
This gene encodes a member of the dual specificity protein kinase family, which functions as a mitogen-activated protein (MAP) kinase kinase. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This protein phosphorylates and activates p38 MAP kinase in response to inflammatory cytokines or environmental stress. As an essential component of p38 MAP kinase mediated signal transduction pathway, this gene is involved in many cellular processes such as stress induced cell cycle arrest, transcription activation and apoptosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
dual specificity mitogen-activated protein kinase kinase 6; kinase 6 (MAP kinase kinase 6); MAPK/ERK kinase 6; MAPKK 6; MAPKK6; MEK 6; MEK6; mitogen-activated; MKK6; PRKMK6; protein kinase; protein kinase, mitogen-activated, kinase 6 (MAP kinase kinase 6); SAPK kinase 3; SAPKK-3; stress-activated protein kinase kinase 3
MAP2K6; MAPKK6; MEK6; MKK6; PRKMK6; SAPKK-3; SAPKK3; SKK3