Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
MA5-11231 targets MMP-11 (Stromelysin-3) in IHC (P), IP, and WB applications and shows reactivity with Human samples.
The MA5-11231 immunogen is recombinant protein corresponding to active form of human MMP-11.
Stromelysin, a member of the matrix metalloproteinase family, demonstrates wide substrate specificity with the ability to degrade proteoglycan, fibronectin, laminin, casein, and the nonhelical region of collagen. The stromelysin-3 (MMP-11) gene was originally identified on the basis that it is expressed specifically in stromal cells surrounding invasive breast carcinomas. MMP-11 is localized by in situ hybridization to the long arm of chromosome 22. The MMP-11 expression is found more specifically in malignant tumors than in benign ones.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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