For reconstitution, we recommend adding 100 µL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiments, we strongly recommend performing another round of desalting. (Zeba Spin Desalting Columns, 7KMWCO, 0.5 mL, Product # 89882)
MGC3207 catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). Independently from catalytic activity, MGC3207 promotes cell invasion in response to constitutive RhoA activation by promoting FAK tyrosine phosphorylation and stress fiber turnover.
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Protein Aliases: M1Pi; Mediator of RhoA-dependent invasion; Methylthioribose-1-phosphate isomerase; methylthioribose-1-phosphate isomerase homolog; MGC3207; MRI1; MTR-1-P isomerase; S-methyl-5-thioribose-1-phosphate isomerase; S-methyl-5-thioribose-1-phosphate isomerase 1; Translation initiation factor eIF-2B subunit alpha/beta/delta-like protein
Gene Aliases: MRDI; MRI1; MTNA; UNQ6390/PRO21135; Ypr118w
UniProt ID: (Human) Q9BV20
Entrez Gene ID: (Human) 84245
Molecular Function: isomerase