Invitrogen
This Antibody was verified by Relative expression to ensure that the antibody binds to the antigen stated.
Applications | Tested Dilution | Publications |
---|---|---|
Western Blot (WB) |
1:500-1:2,000 | - |
ELISA (ELISA) |
1:10,000 | - |
Product Specifications | |
---|---|
Species Reactivity |
Human |
Host/Isotype |
Mouse / IgG1 |
Class |
Monoclonal |
Type |
Antibody |
Clone |
5B11 |
Immunogen |
Purified recombinant fragment of human MSH6 expressed in E. Coli. |
Conjugate |
Unconjugated |
Form |
Liquid |
Concentration |
Conc. Not Determined |
Storage buffer |
ascites |
Contains |
0.03% sodium azide |
Storage conditions |
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
RRID |
AB_11154784 |
MA5-15917 targets MSH6 in WB applications and shows reactivity with Human samples.
The MA5-15917 immunogen is purified recombinant fragment of human MSH6 expressed in E. Coli. .
MA5-15917 detects MSH6 which has a predicted molecular weight of approximately 160kDa.
The DNA mismatch repair MSH2/MSH6 heterodimer is responsible for the detection of DNA damage, and may promote apoptosis in normal cells, thus protecting mammals from ultraviolet-induced malignant transformation and hence the prevention of skin cancer.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: DNA mismatch repair protein Msh6; G/T mismatch-binding protein; GTBP; hMSH6; mutS (E. coli) homolog 6; MutS alpha 160kDa subunit; MutS protein homolog 6; MutS-alpha 160 kDa subunit; MutS-alpha 160kDa subunit; p160; Sperm associated protein; sperm-associated protein
Gene Aliases: GTBP; GTMBP; HNPCC5; HSAP; MSH6; p160
UniProt ID: (Human) P52701
Entrez Gene ID: (Human) 2956
Molecular Function:
DNA metabolism protein
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