|Tested species reactivity||Bovine, Guinea pig, Human, Sheep, Rabbit, Rat|
|Host / Isotype||Mouse / IgG1|
|Immunogen||Bovine myelin basic protein.|
|Storage buffer||tissue culture supernatant diluted in 0.2M tris HCl, pH 7.4, with 5-10% FBS|
|Contains||0.09% sodium azide|
|Storage Conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|Tested Applications||Dilution *|
|ELISA (ELISA)||Assay Dependent|
|Immunohistochemistry (Frozen) (IHC (F))||Assay Dependent|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
MA1-24988 detects Myelin Basic Protein from human, rat, bovine, guinea pig, rabbit, and ovine samples.
MA1-24988 has been successfully used in ELISA and immunohistochemistry (frozen) procedures.
The MA1-24988 immunogen is bovine myelin basic protein.
Myelin is a membrane characteristic of the nervous tissue and functions as an insulator to increase the velocity of the stimuli being transmitted between a nerve cell body and its target. Myelin isolated from human and bovine nervous tissue is composed of approximately 80% lipid and 20% protein, and 30% of the protein fraction constitutes myelin basic protein. MBP is an 'intrinsically unstructured' protein with a high proportion (approximately 75%) of random coil, but postulated to have core elements of beta-sheet and alpha-helix. MBP is a major protein in CNS myelin and is expressed specifically in the nervous system.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.