This gene belongs to a family of glycohydrolytic enzymes which remove sialic acid residues from glycoproteins and glycolipids. Expression studies in COS7 cells confirmed that this gene encodes a functional sialidase. Its cytosolic localization was demonstrated by cell fractionation experiments.
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Protein Aliases: Cytosolic sialidase; N-acetyl-alpha-neuraminidase 2; neuraminidase 2 (cytosolic sialidase); sialidase 2 (cytosolic sialidase); Sialidase-2
Gene Aliases: NEU2; SIAL2
UniProt ID: (Human) Q9Y3R4
Entrez Gene ID: (Human) 4759
Molecular Function: hydrolase