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|Tested species reactivity||Bovine, Horse, Human, Mouse, Non-human primate|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptide (DTDDRHRIEEKRKRKT--AA) of NF-kB p65-NLS protein.|
|Purification||Antigen affinity chromatography|
|Contains||0.05% sodium azide|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
|Immunocytochemistry (ICC)||5 µg/ml|
|Immunofluorescence (IF)||5 µg/ml|
|Immunohistochemistry (Paraffin) (IHC (P))||10 µg/ml|
|Western Blot (WB)||1-3 µg/ml|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
P65 NLS is a transcription factor belonging to NF-kappa B family with the N-terminal Rel homology domain of the NF-kB family, a C-terminal transcription activation domain and a nuclear receptor interaction motif (LXXLL). p65 is a part of the nuclear localization signal (NLS) polypeptide of NF-kB (p50/p65) heterodimer. IkBa the most abundant IkB interacts with active NF-kB p65 homodimers and inactivates their transcriptional potential by trapping them in the cytoplasm and through stable complex formation. It is ubiquitously expressed in most of the tissues.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
C1orf166; E3 SUMO-protein ligase MUL1; E3 ubiquitin ligase; E3 ubiquitin-protein ligase MUL1; GIDE; Growth inhibition and death E3 ligase; MAPL; mitochondria-anchored protein ligase; mitochondrial E3 ubiquitin ligase 1; mitochondrial ubiquitin ligase activator of NF-kB; Mitochondrial ubiquitin ligase activator of NFKB 1; Mitochondrial-anchored protein ligase; MULAN; Putative NF-kappa-B-activating protein 266; RING finger protein 218; RNF218; RP11-401M16.2
0610009K11Rik; AV000801; BOS_2439; C1orf166; GIDE; MAPL; MUL1; MULAN; RNF218