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NPY1R (extracellular) Antibody (ANR-027-200UL) in IHC (F)
Expression of NPY1R in rat striatum and subventricular zone (SVZ) - Immunohistochemical staining of perfusion-fixed frozen rat brain sections with Anti-NPY1R (extracellular) Antibody (#ANR-027), (1:200), followed by goat Anti-rabbit-AlexaFluor-488. NPY1R immunoreactivity (green) appears in the striatum (STR) and the SVZ. Cell nuclei were stained with DAPI (blue). LV = Lateral ventricle.
Product Details
ANR-027-200UL
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
CFDKFPSDSHRLSY, corresponding to amino acid residues 197-210 of mouse NPY1R, 2nd extracellular loop
Conjugate
Form
Lyophilized
Concentration
0.8 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.4, with 1% BSA
Contains
0.05% sodium azide
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Reconstitution: 25 µL, 50 µL or 0.2 mL double distilled water (DDW), depending on the sample size. The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20C. The reconstituted solution can be stored at 4C for up to 1 week. For longer periods, small aliquots should be stored at -20C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).
Target Information
Neuropeptide Y receptors are a class of G-protein coupled receptors which are activated by the closely related peptide horomones neuropeptide Y, peptide YY and pancreatic polypeptide. These receptors are involved in control of a diverse set of behavioral processes including appetite, circadian rhythme, and anxiety.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: FC5; Neuropepetide Y1 Receptor; neuropeptide Y receptor subtype; Neuropeptide Y receptor type 1; neuropeptide Y1 receptor; NPY-1 receptor; NPY-Y1 receptor; NPY1-R; PY receptor Y1
Gene Aliases: NPY-1; NPY1-R; NPY1R; NPYR; NPYY1; Y1-R
UniProt ID: (Human) P25929, (Mouse) Q04573
Entrez Gene ID: (Human) 4886, (Mouse) 18166, (Rat) 29358
outflow tract morphogenesis
glucose metabolic process
cell surface receptor signaling pathway
G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger
adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway
neuropeptide signaling pathway
locomotory behavior
feeding behavior
blood circulation
regulation of blood pressure
sensory perception of pain
peristalsis
response to estradiol
regulation of multicellular organism growth
positive regulation of vasoconstriction
negative regulation of hormone secretion
negative regulation of cytosolic calcium ion concentration
signal transduction
G-protein coupled receptor signaling pathway
chemical synaptic transmission
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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