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NUP50 Antibody (MA5-44733) in IHC (P)
Immunohistochemistry analysis of NUP50 in paraffin-embedded human liver carcinoma tissue. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0) for 2 minutes. The tissues were blocked in 1% BSA for 20 minutes at room temperature, washed with ddH2O and PBS, and then probed with NUP50 Monoclonal antibody (Product # MA5-44733) using a dilution of 1:100 for 1 hour... View More
Product Details
MA5-44733
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293 cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
JE64-06
Immunogen
Recombinant protein within human NUP50 aa 11-110/468.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
TBS, pH 7.4, with 40% glycerol, 0.05% BSA
Contains
0.05% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2931191
Target Information
The nuclear pore complex is a massive structure that extends across the nuclear envelope, forming a gateway that regulates the flow of macromolecules between the nucleus and the cytoplasm. Nucleoporins are the main components of the nuclear pore complex in eukaryotic cells. The protein encoded by this gene is a member of the FG-repeat containing nucleoporins that functions as a soluble cofactor in importin-alpha:beta-mediated nuclear protein import. Pseudogenes of this gene are found on chromosomes 5, 6, and 14. Two transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 50 kDa nucleoporin; CTA-268H5.7; DKFZP564A043; MGC39961; nuclear pore associated protein 60 kDa; Nuclear pore complex protein Nup50; Nuclear pore-associated protein 60 kDa-like; nuclear pore-associated protein 60L; nucleoporin 50 kDa; nucleoporin 50kD; nucleoporin 50kDa; Nucleoporin Nup50; nucleoprotein 50; Nucleoprotein 50kD; NUP50 protein; OTTHUMP00000199530
Gene Aliases: 1700030K07Rik; AI413123; NPAP60; NPAP60L; NUP50; PRO1146; Rtp60
UniProt ID: (Human) Q9UKX7, (Rat) O08587, (Mouse) Q9JIH2
Entrez Gene ID: (Human) 10762, (Rat) 25497, (Mouse) 18141
mRNA export from nucleus
tRNA export from nucleus
protein import into nucleus
mitotic nuclear envelope disassembly
regulation of glucose transport
viral process
protein sumoylation
viral transcription
gene silencing by RNA
intracellular transport of virus
regulation of cellular response to heat
neural tube formation
protein transport
intracellular transport
mRNA transport
nucleocytoplasmic transport
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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