Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Invitrogen
Naja kaouthia Cobra Venom Factor Polyclonal Antibody
Product Details
PA5-117705
| Applications | Tested Dilution | Publications |
|---|---|---|
Western Blot (WB) |
1:500-1:5,000 | - |
| Product Specifications | |
|---|---|
Species Reactivity |
Reptile |
Host/Isotype |
Rabbit / IgG |
Class |
Polyclonal |
Type |
Antibody |
Immunogen |
Recombinant Naja kaouthia Cobra venom factor protein (733-984aa) |
Conjugate |
Unconjugated |
Form |
Liquid |
Concentration |
5 mg/mL |
Purification |
Protein G |
Storage buffer |
10mM PBS, pH 7.4, with 50% glycerol |
Contains |
0.03% ProClin 300 |
Storage conditions |
-20°C or -80°C if preferred |
RRID |
AB_2902334 |
Product Specific Information
This antibody has been tested in direct-ELISA
Target Information
Complement-activating protein in cobra venom. It is a structural and functional analog of complement component C3b, the activated form of C3. It binds factor B (CFB), which is subsequently cleaved by factor D (CFD) to form the bimolecular complex CVF/Bb. CVF/Bb is a C3/C5 convertase that cleaves both complement components C3 and C5. Structurally, it resembles the C3b degradation product C3c, which is not able to form a C3/C5 convertase. Unlike C3b/Bb, CVF/Bb is a stable complex and completely resistant to the actions of complement regulatory factors H (CFH) and I (CFI). Therefore, CVF continuously activates complement resulting in the depletion of complement activity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Have you cited this product in a publication?
Let us know so we can reference it here.
Bioinformatics
Protein Aliases: CVF
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support