|Tested species reactivity||Human, Mouse, Rat|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptide corresponding to amino acids 221-270 of human Neurexophilin-4|
|Purification||Antigen affinity chromatography|
|Storage buffer||PBS, pH 7.2|
|Contains||0.05% sodium azide|
|Storage Conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|Tested Applications||Dilution *|
|Immunohistochemistry (Paraffin) (IHC (P))||1:50-1:200|
|Western Blot (WB)||1:500-1:1000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
This antibody detects endogenous protein at a molecular weight of 33 kDa.
Purity is >95% by SDS-PAGE.
Members of the Neurexophilin family are neuropeptide-like glycoproteins that undergo proteolytic processing after synthesis. As secreted proteins, Neurexophilins are thought to function as signaling molecules which specifically bind to target proteins, such as neurexin I-alpha (a protein that promotes adhesion between dendrites and axons), and are essential for proper neurotransmitter release. Neurexophilins contain five common domains including a variable N-terminal domain, a highly conserved N-glycosylated central domain, a short linker region and a cysteine-rich conserved C-terminal domain. Neurexophilin-4, also known as NXPH4 or NPH4, is a 308 amino acid secreted protein belonging to the neurexophilin family. Neurexophilin-4 is expressed in brain, spleen and testis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.