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|Tested species reactivity||Human|
|Published species reactivity||Avian, Rabbit, Rat|
|Host / Isotype||Mouse / IgG1|
|Immunogen||Human neurofilament preparation|
|Contains||0.09% sodium azide|
|Storage Conditions||4°C or -20°C if preferred|
|Tested Applications||Dilution *|
|Immunohistochemistry (Frozen) (IHC (F))||1:25-1:200|
|Immunohistochemistry (Paraffin) (IHC (P))||1:25-1:200|
|Western Blot (WB)||1:100-1:1000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
|Immunohistochemistry (IHC)||See 5 publications below|
MA1-06803 detects neurofilament 70 kDa in human samples.
MA1-06803 has sucessfully been used in Western blotting, and immunohistochemistry procedures. By Western blot it detects a 70 kDa band representing neurofilament ~70 kDa.
The MA1-06803 immunogen is a human neurofilament preparation.
Like most other intermediate filament proteins (IFPs), the expression of the different neuronal IFPs is both tissue-specific and developmentally regulated. The neurofilament (NF) triplet proteins (~70, 160, and 200 kDa) occur in both the central and
peripheral nervous system and are normally restricted to neurons. The 70 kDa NF-protein can self-assemble into a filamentous structure, whereas the 160 kDa and 200 kDa NF-proteins require the presence of the 70 kDa NF-protein to co-assemble.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Promotional effects of vasoactive intestinal peptide on the development of rodent Hertwig's epithelial root sheath.
MA1-06803 was used in immunohistochemistry to study the potential role of vasoactive intestinal peptide in rodent Hertwig's epithelial root sheath development
|Xu J,Kawashima N,Fujiwara N,Harada H,Ota MS,Suda H||Congenital anomalies (52:162)||2012|
Free radical damage as a biomarker of bladder dysfunction after partial outlet obstruction and reversal.
MA1-06803 was used in immunohistochemistry to study protein carbonylation and nitrotyrosination as a biomarker of dysfunction after partial bladder outlet obstruction.
|Lin WY,Guven A,Juan YS,Neuman P,Whitbeck C,Chichester P,Kogan B,Levin RM,Mannikarottu A||BJU international (101:621)||2008|
Effects of L-arginine and L-NAME on chronic partial bladder outlet obstruction in rabbit.
MA1-06803 was used in immunohistochemistry to investigate the impact of nitric oxide synthase and blook flow on the severity of damages caused by acute and chronic partial bladder outlet obstruction
|Lin WY,Levin RM,Chichester P,Leggett R,Juan YS,Johnson A,Neumann P,Whitbeck C,Guven A,Kogan B,Mannikarottu A||American journal of physiology. Regulatory, integrative and comparative physiology (293:R2390)||2007|
Electrophysiological measurements in three-dimensional in vivo-mimetic organotypic cell cultures: preliminary studies with hen embryo brain spheroids.
MA1-06803 was used in immunohistochemistry to investigate the electrophysiological properties of three-dimensional hen embryo brain spheroids
|Uroukov IS,Ma M,Bull L,Purcell WM||Neuroscience letters (404:33)||2006|
L-NAME, a nitric oxide synthase inhibitor, diminishes oxidative damage in urinary bladder partial outlet obstruction.
MA1-06803 was used in immunohistochemistry to investigate the effect of the nitric oxide synthase inhibitor L-NAME on oxidative damage
|Conners W,Whitebeck C,Chicester P,Legget R,Lin AD,Johnson A,Kogan B,Levin R,Mannikarottu A||American journal of physiology. Renal physiology (290:F357)||2006|
70 kDa neurofilament protein; CMT1F; CMT2E; light molecular weight neurofilament protein; neurofilament protein, light chain; neurofilament subunit NF-L; Neurofilament triplet L pro; neurofilament triplet L protein; neurofilament, light polypeptide 68kDa; NFL; NLC; protein phosphatase 1, regulatory subunit 110
CMT1F; CMT2E; NEFL; NF-L; NF68; NFL; PPP1R110