PA1-4395 detects NKX3.1 from human samples.
PA1-4395 has been successfully used in Western blot procedures.
PA1-4395 immunizing peptide corresponds to amino acid residues 21-37 from human NKX3.1 protein.
NKX3.1 is a homeobox gene which exhibits prostate and testis specific expression. Loss of NKX3.1 expression has been implicated in prostate development and tumorigenesis. NKX3.1 expression is dramatically down-regulated in testicular cancer of germ cell origin. Results suggest that NKX3.1 is essential for normal testis function and that its loss of expression is highly associated with the invasive phenotype of testicular germ cell tumors.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Homeobox protein NK-3 homolog A; Homeobox protein Nkx-3.1; NK homeobox, family 3, A; NK3 transcription factor homolog A; NK3 transcription factor related, locus 1
Gene Aliases: BAPX2; NKX3; NKX3-1; NKX3.1; NKX3A
UniProt ID: (Human) Q9HBG0
Entrez Gene ID: (Human) 4824