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Invitrogen
OPA1-15269 detects the beta 2 adrenergic receptor from human samples. OPA1-15269 has been successfully used in immunohistochemistry procedures. By immunohistochemistry, OPA1-15269 detects the beta-2 adrenergic receptor in formalin fixed, paraffin embedded human tissues. The OPA1-15269 immunogen is a Synthetic peptide, KLH conjugated, corresponding to the extracellular N-terminus of human beta 2 Andrenergic receptor.
Store at 4ºC short term. For extended storage aliquot and store at -20ºC or below. Avoid freeze/thaw cycles.
Adrenergic receptors (ARs) are members of the 7-transmembrane domain G-protein-coupled receptor superfamily that bind the endogenous catecholamines epinephrine and norepinephrine. Pharmacological, structural, and molecular cloning data indicate significant heterogeneity within this receptor family. Nine receptor subtypes have been identified thus far including three alpha-1 AR subtypes (1A/D, 1B, and 1C), three alpha-2 ARs (2A, 2B, and 2C), and three beta AR subtypes (1, 2, and 3). ARs participate in either the onset or maintenance of several disease states including hypertension, cardiac dysfunction (congestive heart failure, ischemia, arrhythmias), diabetes, glaucoma, depression, and impotence.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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