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|Tested species reactivity||Mouse|
|Published species reactivity||Bovine, Sheep, Mouse, Human|
|Host / Isotype||Rat / IgG2a|
|Immunogen||This antibody reacts with pro and active MMP-2 protein.|
|Purification||Ammonium sulfate precipitation, Ion-exchange chromatography|
|Storage buffer||PBS with 1% BSA|
|Storage Conditions||4° C|
|Tested Applications||Dilution *|
|ELISA (ELISA)||Assay Dependent|
|Inhibition Assays (IA)||Assay Dependent|
|Immunofluorescence (IF)||Assay Dependent|
|Immunohistochemistry (IHC)||Assay Dependent|
|Western Blot (WB)||Assay Dependent|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
This gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. This gene is located in a six-cadherin cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer. In addition, aberrant expression of this protein is observed in cervical adenocarcinomas. Mutations in this gene have been associated with congential hypotrichosis with juvenile macular dystrophy.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
|Mouse||1:200||Keratin 79 identifies a novel population of migratory epithelial cells that initiates hair canal morphogenesis and regeneration.||Veniaminova NA,Vagnozzi AN,Kopinke D,Do TT,Murtaugh LC,Maillard I,Dlugosz AA,Reiter JF,Wong SY||Development (Cambridge, England) (140:4870)||2013|
|WT1-interacting protein and ZO-1 translocate into podocyte nuclei after puromycin aminonucleoside treatment.||Rico M,Mukherjee A,Konieczkowski M,Bruggeman LA,Miller RT,Khan S,Schelling JR,Sedor JR||American journal of physiology. Renal physiology (289:F431)||2005|
||Conditional targeting of E-cadherin in skin: insights into hyperproliferative and degenerative responses.||Tinkle CL,Lechler T,Pasolli HA,Fuchs E||Proceedings of the National Academy of Sciences of the United States of America (101:552)||2004|
BMI1 represses Ink4a/Arf and Hox genes to regulate stem cells in the rodent incisor.
13-2000Z was used in immunohistochemistry - paraffin section to study BMI-mediated repression of Hox genes in stem cells.
|Biehs B,Hu JK,Strauli NB,Sangiorgi E,Jung H,Heber RP,Ho S,Goodwin AF,Dasen JS,Capecchi MR,Klein OD||Nature cell biology (15:846)||2013|
Cadherin expression in the developing mouse olfactory system.
13-2000Z was used in immunohistochemistry to report the localization of classical cadherins in the developing olfactory system.
|Akins MR,Benson DL,Greer CA||The Journal of comparative neurology (501:483)||2007|
|Mouse||Not Cited||Links between signal transduction, transcription and adhesion in epithelial bud development.||Jamora C,DasGupta R,Kocieniewski P,Fuchs E||Nature (422:317)||2003|
|Mouse||Not Cited||Conditional targeting of E-cadherin in skin: insights into hyperproliferative and degenerative responses.||Tinkle CL,Lechler T,Pasolli HA,Fuchs E||Proceedings of the National Academy of Sciences of the United States of America (101:552)||2004|
cadherin-3; calcium-dependent adhesion protein; CDHP; HJMD; PCAD; placental; placental cadherin; RPE-specific cadherin
AI385538; Cadp; Cdh3; Cdhp; P-cadherin; Pcad