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PA1-25695 detects RGS17 / RGSZ2 from human, mouse, and rat samples.
PA1-25695 has been successfully used in Western blot procedures. It has a predicted molecular weight of 25 kDa.
The PA1-25695 immunogen is a synthetic peptide corresponding to residues 41-100 of RGS17.
Store at 4ºC short term. For extended storage, store at -20ºC, avoiding freeze/thaw cycles.
This gene encodes a member of the regulator of G-protein signaling family. This protein contains a conserved, 120 amino acid motif called the RGS domain and a cysteine-rich region. The protein attenuates the signaling activity of G-proteins by binding to activated, GTP-bound G alpha subunits and acting as a GTPase activating protein (GAP), increasing the rate of conversion of the GTP to GDP. This hydrolysis allows the G alpha subunits to bind G beta/gamma subunit heterodimers, forming inactive G-protein heterotrimers, thereby terminating the signal.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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