Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
PA1-27669 detects LMAN1 from human samples.
PA1-27669 may be successfully used in Western blot applications. By Western blot, this antibody has only been tested on fusion protein.
The PA1-27494 immunogen is a synthetic peptide corresponding to human ERGIC-53 protein.
The protein encoded by this gene is a type I integral membrane protein localized in the intermediate region between the endoplasmic reticulum and the Golgi, presumably recycling between the two compartments. The protein is a mannose-specific lectin and is a member of a novel family of plant lectin homologs in the secretory pathway of animal cells. Mutations in the gene are associated with a coagulation defect. Using positional cloning, the gene was identified as the disease gene leading to combined factor V-factor VIII deficiency, a rare, autosomal recessive disorder in which both coagulation factors V and VIII are diminished.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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