PA1-29792 detects POR from mouse, monkey, human, rat, canine, guinea pig, hamster, porcine, rabbit and sheep samples.
PA1-29792 has been successfully used in Western blot applications. Suggested positive controls for this product are rat liver, NADPH, cytochrome, P450 and reductase protein.
The PA1-29792 immunogen is purified rat liver NADPH-Cytochrome P450 reductase.
This gene encodes an endoplasmic reticulum membrane oxidoreductase with an FAD-binding domain and a flavodoxin-like domain. The protein binds two cofactors, FAD and FMN, which allow it to donate electrons directly from NADPH to all microsomal P450 enzymes. Mutations in this gene have been associated with various diseases, including apparent combined P450C17 and P450C21 deficiency, amenorrhea and disordered steroidogenesis, congenital adrenal hyperplasia and Antley-Bixler syndrome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: CPR; CYPOR; cytochrome P450 reductase; DKFZp686G04235; FLJ26468; NADPH--cytochrome P450 reductase; NADPH-cytochrome P-450 oxidoreductase; NADPH-cytochrome P450 oxidoreductase; NADPH-cytochrome P450 reductase; NADPH-dependent cytochrome P450 reductase; P450 (cytochrome) oxidoreductase; P450R
Gene Aliases: 4933424M13Rik; CPR; CYPOR; I79_007261; P450R; POR