Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
PA1-4133 detects heavy neurofilament subunit tail in human samples.
PA1-4133 has been successfully used in Western blot procedures.
The PA1-4133 immunogen is a synthetic peptide corresponding to residues S P E K A K S P E K A K S, which is a repeated motif of human NFH.
Involved in the maintenance of neuronal caliber, neurofilaments are the intermediate filament proteins found specifically in neurons, and are composed predominantly of three major proteins called NF-L, NF-M and NF-H. Like most other intermediate filament proteins (IFPs), the expression of the different neuronal IFPs is both tissue-specific and developmentally regulated. NF-H has an important role in mature axons and is involved in amyotrophic lateral sclerosis (ALS).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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