Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
PA1-74064 detects Antithrombin from human samples.
PA1-74064 has been successfully used in ELISA applications.
The PA1-74064 immunogen is Antithrombin from human plasma.
The protein encoded by this gene is a plasma protease inhibitor and a member of the serpin superfamily. This protein inhibits thrombin as well as other activated serine proteases of the coagulation system, and it regulates the blood coagulation cascade. The protein includes two functional domains: the heparin binding-domain at the N-terminus of the mature protein, and the reactive site domain at the C-terminus. The inhibitory activity is enhanced by the presence of heparin. More than 120 mutations have been identified for this gene, many of which are known to cause antithrombin-III deficiency.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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