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Antibody detects endogenous levels of total TIAL1.
The protein encoded by this gene is a member of a family of RNA-binding proteins, has three RNA recognition motifs (RRMs), and binds adenine and uridine-rich elements in mRNA and pre-mRNAs of a wide range of genes. It regulates various activities including translational control, splicing and apoptosis. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. The different isoforms have been show to function differently with respect to post-transcriptional silencing.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: aging-associated gene 7 protein; Nucleolysin TIAR; RNA binding protein TIAR (TIA-1 related); T-cluster binding protein; TIA-1-related nucleolysin; TIA-1-related protein; Tial 1 cytotoxic granule-associated RNA- binding protein-like 1; Tial1 cytotoxic granule-associated RNA binding protein-like 1; Tial1 cytotoxic granule-associated RNA-binding protein-like 1
Gene Aliases: 5330433G13Rik; AL033329; mTIAR; TCBP; TIAL1; TIAR
UniProt ID: (Human) Q01085, (Mouse) P70318
Entrez Gene ID: (Human) 7073, (Rat) 361655, (Mouse) 21843
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