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ANO5 Antibody (PA5-109393) in WB
Western blot analysis of ANO5 in extracts of various cell lines. Samples were incubated with ANO5 Polyclonal antibody (Product # PA5-109393) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 5s.
Product Details
PA5-109393
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human ANO5 (NP_998764.1).
Conjugate
Form
Liquid
Concentration
1.8 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.01% thimerosal
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
RRID
AB_2854804
Product Specific Information
Immunogen sequence: MGDPDLLEVL AEEGEKVNKH IDYSFQMSEQ SLSSRETSFL INEETMPAKR FNLFLRRRLM FQKNQQSKDS IFFRDGIRQI DFVLSYVDDV KKDAELKAER RKEFETNLRK TGLELEIEDK RDSEDGRTYF VKIHAPWEVL VTYAEVLGIK MPIKESDIPR PKHTPISYVL GPVRLPLSVK YPHPEYFTAQ FSRHRQELFL IEDQATFFPS SSRNRIVYYI LSRCPFGIED GKKRFGIERL LNSNTYSSAY PLHDGQYWKP SEPPNPTNER YTLHQNWARF SYFYKEQPLD LIKNYYGEKI
Target Information
Ano5 does not exhibit calcium-activated chloride channel (CaCC) activity. The Ano5 gene encodes a member of the anoctamin family of transmembrane proteins. The Ano5 protein is likely a calcium activated chloride channel. Mutations in the Ano5 gene have been associated with gnathodiaphyseal dysplasia. Alternatively spliced transcript variants have been described for Ano5. Diseases associated with ANO5 include Gnathodiaphyseal Dysplasia and Miyoshi Muscular Dystrophy 3.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: anoctamin 5; Anoctamin-5; Gnathodiaphyseal dysplasia 1 protein; Gnathodiaphyseal dysplasia 1 protein homolog; integral membrane protein GDD1; Transmembrane protein 16E
Gene Aliases: 9330162L24; ANO5; GDD1; LGMD2L; RGD1564265; TMEM16E
UniProt ID: (Human) Q75V66, (Mouse) Q75UR0
Entrez Gene ID: (Human) 203859, (Mouse) 233246, (Rat) 308637
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