Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Immunogen sequence: EQPKGEELSA AAIKRIVATA KASGKKLQKV TLKVSPRGII LTDNLTNQLI ENVSIYRISY CTADKMHDKV FAYIAQSQHN QSLECHAFLC TKRKMAQAVT LTVAQAFKVA FEFWQVSKEE KEKRDKASQE GGDVLGARQD CTPSLKSLVA TGNLLDLEET AKAPLSTVSA NTTNMDEVPR PQALSGSSVV WELDDGLDEA FSRLAQSRTN PQVLDTGLTA QDMHYAQCLS PVDWDKPDSS GTEQDDLFSF
The protein encoded by this gene is a cytosolic protein which contains a phosphotyrosine binding (PTD) domain. The PTD domain has been found to interact with the cytoplasmic tail of the LDL receptor. Mutations in this gene lead to LDL receptor malfunction and cause the disorder autosomal recessive hypercholesterolaemia.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Autosomal recessive hypercholesterolemia protein; Autosomal recessive hypercholesterolemia protein homolog; DKFZp586D0624; LDL receptor adaptor protein; Low density lipoprotein receptor adapter protein 1; MGC34705; RP11-70P17.2
Gene Aliases: AA691260; ARH; ARH1; ARH2; FHCB1; FHCB2; LDLRAP1; RGD1563417
UniProt ID: (Human) Q5SW96, (Mouse) Q8C142
Entrez Gene ID: (Human) 26119, (Rat) 500564, (Mouse) 100017
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn moreGet expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support