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Product Details
PA5-121244
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 20-114 of human S100A9 (NP_0029561)
Conjugate
Form
Liquid
Concentration
0.69 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.09% sodium azide
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
RRID
AB_2914816
Product Specific Information
Positive test controls include: THP-1, U-937, Mouse lung, Rat spleen. The target is usually found in the following locations: Cell membrane, Cytoplasm, Peripheral membrane protein, Secreted, cytoskeleton.
Immunogen sequence: HQYSVKLGHP DTLNQGEFKE LVRKDLQNFL KKENKNEKVI EHIMEDLDTN ADKQLSFEEF IMLMARLTWA SHEKMHEGDE GPGHHHKPGL GEGTP
Target Information
S100A9 (MRP-14) is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in the inhibition of casein kinase and altered expression of this protein is associated with the disease cystic fibrosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: BM-009; calgranulin B; Calgranulin-B; Calprotectin L1H subunit; DKFZp686B04128; intracellular calcium-binding protein (MRP14); Leukocyte L1 complex heavy chain; Macrophage; Migration inhibitory factor-related protein 14; Monocyte; MRP-14; MRP15; MRP16; Myeloid-related protein 14; p14; Protein S100-A9; S100 A9; S100 calcium binding protein A9 (calgranulin B); S100 calcium-binding protein A9; S100 calcium-binding protein A9 (calgranulin B)
Gene Aliases: 60B8AG; AW546964; BEE22; CAGB; CFAG; CGLB; GAGB; L1AG; LIAG; MAC387; MIF; MRP14; NIF; P14; S100A9
UniProt ID: (Human) P06702, (Mouse) P31725, (Rat) P50116
Entrez Gene ID: (Human) 6280, (Mouse) 20202, (Rat) 94195
cytokine production
leukocyte migration involved in inflammatory response
positive regulation of peptide secretion
regulation of translation
autophagy
apoptotic process
activation of cysteine-type endopeptidase activity involved in apoptotic process
inflammatory response
signal transduction
cell-cell signaling
astrocyte development
positive regulation of blood coagulation
positive regulation of cell growth
neutrophil chemotaxis
actin cytoskeleton reorganization
sequestering of zinc ion
chemokine production
peptidyl-cysteine S-trans-nitrosylation
defense response to bacterium
innate immune response
regulation of integrin biosynthetic process
positive regulation of inflammatory response
defense response to fungus
positive regulation of NF-kappaB transcription factor activity
regulation of cytoskeleton organization
neutrophil aggregation
cellular oxidant detoxification
positive regulation of intrinsic apoptotic signaling pathway
immune system process
chemotaxis
peptidyl-cysteine S-nitrosylation
leukocyte chemotaxis
regulation of inflammatory response
chronic inflammatory response
response to zinc ion
response to lipopolysaccharide
response to ethanol
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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