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Gently mix before use. Optimal concentrations and conditions for each application should be determined by the user.
Immunogen sequence: KLREDQVEMA DYALKSAGAS IIEAGTSESY KNNKAKLYWH GIGFLNHEMP PDIILQPDVY PGKCWAFPGS QGHTLIKLAT KIIPTAVTME HISEKVSPSG
As a probable component of the LINC (LInker of Nucleoskeleton and Cytoskeleton) complex, involved in the connection between the nuclear lamina and the cytoskeleton. The nucleocytoplasmic interactions established by the LINC complex play an important role in the transmission of mechanical forces across the nuclear envelope and in nuclear movement and positioning. May be involved in nuclear remodeling during sperm head formation in spermatogenenis. A probable SUN3:SYNE1 LINC complex may tether spermatid nuclei to posterior cytoskeletal structures such as the manchette.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: hypothetical protein MGC33329; Sad1 and UNC84 domain containing 1; Sad1/unc-84 domain-containing protein 1; SUN domain-containing protein 3
Gene Aliases: SUN3; SUNC1
UniProt ID: (Human) Q8TAQ9
Entrez Gene ID: (Human) 256979
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