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This antibody is predicted to react with bovine and canine based on sequence homology.
This antibody is tested in Peptide ELISA: antibody detection limit dilution 4,000.
FEM1A (FEM-1 homolog a), also known as EPRAP (Prostaglandin E receptor 4-associated protein), is a 669 amino acid cytoplasmic protein that belongs to the FEM-1 family. FEM1A is present in atheromata and in macrophages derived from peripheral blood monocytes. FEM1A may be a component of an E3 ubiquitin-protein ligase complex and functions as a substrate recognition subunit. It is suggested that FEM1A participates in anti-inflammatory signaling of macrophages via its interaction with EP4. FEM1A is down-regulated in Rhabdomyosarcoma, the most common soft tissue neoplasm of children. FEM1A is considered a candidate gene for polycystic ovary syndrome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: DKFZp762M136; FEM1-alpha; FEM1a; Prostaglandin E receptor 4-associated protein; Protein fem-1 homolog A
Gene Aliases: EPRAP; FEM1A
UniProt ID: (Human) Q9BSK4
Entrez Gene ID: (Human) 55527
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