This antibody is predicted to react with canine, mouse, porcine and rat based on sequence homology.
This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs , which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbls class and, in addition to an F-box, contains several tandem leucine-rich repeats and is localized in the nucleus.
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Protein Aliases: F-box and leucine-rich repeat protein 3; F-box and leucine-rich repeat protein 3A; F-box protein Fbl3a; F-box/LRR-repeat protein 3; F-box/LRR-repeat protein 3A; FBL3; FBL3A; FBXL3; FBXL3A
Gene Aliases: FBL3; FBL3A; FBXL3; FBXL3A
UniProt ID: (Human) Q9UKT7
Entrez Gene ID: (Human) 26224