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A suggested positive control is human spleen tissue lysate.
PA5-21094 can be used with blocking peptide PEP-1208.
FBXL16 (F-box and leucine-rich repeat protein 16), a member of the F-box protein family, is a probable substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex. It is characterized by an approximately 40-amino acid F-box motif. F-box proteins interact with SKP1 through the F-box, and they interact with ubiquitination targets through other protein interaction domains. FBXL16 is a novel E2F1-regulated gene in crucial cell cycle regulation pathways.
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Protein Aliases: c380A1.1 (novel protein); F-box and leucine-rich repeat protein 16; F-box/LRR-repeat protein 16; spinal cord injury and regeneration related 1; Spinal cord injury and regeneration-related protein 1
Gene Aliases: BC042620; C16orf22; c380A1.1; FBL16; FBXL16; Scirr1
UniProt ID: (Human) Q8N461, (Mouse) A2RT62, (Rat) Q5MJ12
Entrez Gene ID: (Human) 146330, (Mouse) 214931, (Rat) 494223
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