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PA5-21276 targets MUS81 in IF, ICC and WB applications and shows reactivity with Human, Rat and mouse samples.
The PA5-21276 immunogen is recombinant protein fragment contain a sequence corresponding to a region within amino acids 196 and 370 (Q96NY9) of MUS81.
Interacts with EME1 and EME2 to form a DNA structure-specific endonuclease with substrate preference for branched DNA structures with a 5'-end at the branch nick. Typical substrates include 3'-flap structures, replication forks and nicked Holliday junctions. May be required in mitosis for the processing of stalled or collapsed replication forks.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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