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This antibody is predicted to react with Xenopus and zebrafish based on sequence homology.
Mouse Unc119b is related closely to Unc119, a homolog of C. elegans unc119 protein which was first discovered in C. elegans on the basis of a spontaneous mutation affecting locomotion, feeding behavior and chemosensation. Mouse Unc119b shares 90% sequence identity with human UNC119b protein. UNC119b is a myristoyl-binding protein that acts as a cargo adapter: specifically binds the myristoyl moiety of a subset of N-terminally myristoylated proteins and is required for their localization. Myristoyl-binding activity of UNC119b is required to localize NPHP3 to the primary cilium.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: POC7 centriolar protein homolog B; Protein unc-119 homolog B; unc-119 homolog B; unc119 homolog B
Gene Aliases: AA407659; AI414892; POC7B; UNC119B
UniProt ID: (Human) A6NIH7, (Mouse) Q8C4B4
Entrez Gene ID: (Human) 84747, (Mouse) 106840
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