Recommended positive controls: A431, H1299, HeLaS3, HepG2, Raji.
Predicted reactivity: Mouse (94%), Rat (94%), Xenopus laevis (86%), Chicken (91%), Bovine (97%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
The protein encoded by this gene is a serine/threonine protein kinase that activates the p38/MAPK14 stress-activated MAPK cascade but inhibits the basal activity of the MAPK8/JNK cascade. The encoded protein is a member of the GCK subfamily of STE20-like kinases.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
Protein Aliases: CTCL-associated antigen HD-CL-09; Cutaneous T-cell lymphoma-associated antigen HD-CL-09; Dendritic cell-derived protein kinase; DKFZp666H245; EC 188.8.131.52; FLJ31808; hKFC-A; JNK/SAPK-inhibitory kinase; Jun kinase-inhibitory kinase; Kinase from chicken homolog A; Serine/threonine-protein kinase TAO3; STE2-like kinase; STE20-like kinase; tao; Thousand and one amino acid protein 3
Gene Aliases: DPK; JIK; KDS; MAP3K18; TAOK3
UniProt ID: (Human) Q9H2K8
Entrez Gene ID: (Human) 51347