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Recommended positive controls: NIH-3T3, THP-1.
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
CCRL2 (C-C chemokine receptor-like 2), also known as chemokine receptor X, human chemokine receptor (HCR), CRAM-A or CRAM-B, is a seven pass transmembrane protein expressed by monocytes, neutrophils, and dendritic cells of immunal tissues (predominanly spleen, fetal liver, bone marrow and lymph node). It shares over 40% homology with other C-C chemokine receptors but does not share the conserved DRY motif which is among the important motifs necessary for signalling and ligand-binding. C-C chemokine receptors are G-protein coupled, seven pass transmembrane domain proteins whose major physiological role is to function in the chemotaxis of T cells and phagocytic cells to areas of inflammation.
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For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: atypical chemokine receptor 5; C-C chemokine receptor-like 2; chemokine (C-C motif) receptor-like 2; Chemokine receptor CCR11; Chemokine receptor X; G-protein coupled beta chemokine receptor; L-CCR; Lipopolysaccharide-inducible C-C chemokine receptor; MGC116710; Putative MCP-1 chemokine receptor
Gene Aliases: 1810047I05Rik; ACKR5; CCR11; CCR6; CCRL2; CKRX; Cmkbr1l2; CRAM; CRAM-A; CRAM-B; E01; HCR; L-CCR; Lccr
UniProt ID: (Human) O00421, (Mouse) O35457
Entrez Gene ID: (Human) 9034, (Mouse) 54199
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