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Recommended positive controls: A431, Jurkat, Raji, mouse brain.
Predicted reactivity: Mouse (100%), Rat (100%), Zebrafish (91%), Bovine (100%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Heterotrimeric guanine nucleotide-binding proteins (G proteins), which integrate signals between receptors and effector proteins, are composed of an alpha, a beta, and a gamma subunit. These subunits are encoded by families of related genes. This gene encodes a beta subunit. Beta subunits are important regulators of alpha subunits, as well as of certain signal transduction receptors and effectors. This gene contains a trinucleotide (CCG) repeat length polymorphism in its 5' UTR.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: G protein subunit beta-2; G protein, beta-2 subunit; guanine nucleotide binding protein (G protein), beta polypeptide 2; guanine nucleotide binding protein, beta 2; guanine nucleotide-binding protein G(I)/G(S)/G(T) beta subunit 2; Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2; guanine nucleotide-binding protein, beta-2 subunit; signal-transducing guanine nucleotide-binding regulatory protein beta subunit; Transducin beta chain 2
Gene Aliases: Gnb-2; GNB2
UniProt ID: (Human) P62879, (Mouse) P62880
Entrez Gene ID: (Human) 2783, (Mouse) 14693
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