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Recommended positive controls: 293T, A549, HeLa, HepG2, HCT116.
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Retinoids exert biologic effects such as potent growth inhibitory and cell differentiation activities and are used in the treatment of hyperproliferative dermatological diseases. These effects are mediated by specific nuclear receptor proteins that are members of the steroid and thyroid hormone receptor superfamily of transcriptional regulators. RARRES1, RARRES2, and RARRES3 are genes whose expression is upregulated by the synthetic retinoid tazarotene. RARRES3 is thought act as a tumor suppressor or growth regulator.
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Protein Aliases: HRAS-like suppressor 4; HRSL4; Phospholipase A and acyltransferase 4; RAR-responsive protein TIG3; retinoic acid receptor responder (tazarotene induced) 3; Retinoic acid receptor responder protein 3; retinoic acid-inducible gene 1; Retinoid-inducible gene 1 protein; Tazarotene-induced gene 3 protein
Gene Aliases: HRASLS4; HRSL4; PLA1/2-3; PLAAT4; RARRES3; RIG1; TIG3
UniProt ID: (Human) Q9UL19
Entrez Gene ID: (Human) 5920
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