Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Invitrogen
Recommended positive controls: Raji.
Predicted reactivity: Mouse (89%), Rat (90%), Bovine (90%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This protein contains 5 WD repeats, and has a structural similarity with actin-binding proteins: the D. discoideum coronin and the human p57 protein, suggesting that this protein may also be an actin-binding protein that regulates cell motility. Alternative splicing of this gene generates 2 transcript variants.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: coronin, actin binding protein, 2A; coronin, actin-binding protein, 2A; Coronin-2A; coronin-like protein B; IR10; WD protein IR10; WD repeat-containing protein 2; WD-repeat protein 2
Gene Aliases: CLIPINB; CORO2A; IR10; WDR2
UniProt ID: (Human) Q92828
Entrez Gene ID: (Human) 7464
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