Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Recommended positive controls: HeLa.
Predicted reactivity: Mouse (99%), Rat (98%), Zebrafish (95%), Xenopus laevis (98%), Chicken (98%), Bovine (99%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
This gene encodes subunit 2 of the splicing factor 3a protein complex. The splicing factor 3a heterotrimer includes subunits 1, 2 and 3 and is necessary for the in vitro conversion of 15S U2 snRNP into an active 17S particle that performs pre-mRNA splicing. Subunit 2 interacts with subunit 1 through its amino-terminus while the single zinc finger domain of subunit 2 plays a role in its binding to the 15S U2 snRNP. Subunit 2 may also function independently of its RNA splicing function as a microtubule-binding protein.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: pre-mRNA splicing factor SF3A, subunit 2; SAP 62; SF3a66; spliceosome associated protein 62; Spliceosome-associated protein 62; Splicing factor 3A subunit 2; splicing factor 3a, subunit 2, 66kD; splicing factor 3a, subunit 2, 66kDa
Gene Aliases: PRP11; PRPF11; SAP62; SF3A2; SF3a66
UniProt ID: (Human) Q15428
Entrez Gene ID: (Human) 8175
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