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Recommended positive controls: A549, HeLa.
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
NEK11 (FLJ23495) belongs to the NIMA family of kinases which are involved in DNA replication and genotoxic stress response. NEK11 encodes a member of the never in mitosis gene A family of kinases. The encoded protein localizes to the nucleoli, and may function with NEK2A in the S-phase checkpoint. The encoded protein appears to play roles in DNA replication and response to genotoxic stress. Alternatively spliced transcript variants have been described.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Never in mitosis A-related kinase 11; NIMA (never in mitosis gene a)- related kinase 11; NimA-related protein kinase 11; Serine/threonine-protein kinase Nek11
Gene Aliases: NEK11
UniProt ID: (Human) Q8NG66
Entrez Gene ID: (Human) 79858
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