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PA5-34611 targets Chp1 in ChIP and WB applications and shows reactivity with Yeast samples.
The PA5-34611 immunogen is synthetic peptide conjugated to KLH derived from within residues 900 to the C-terminus of Schizosaccharomyces pombe Chp1.
PA5-34611 detects Chp1 which has a predicted molecular weight of approximately 109 kDa.
Regulates centrosome duplication, probably by inhibiting the kinase activity of ROCK2. Proposed to act as co-chaperone for HSP90. May play a role in the regulation of NOD1 via a HSP90 chaperone complex. In vitro, has intrinsic chaperone activity. This function may be achieved by inhibiting association of ROCK2 with NPM1. Involved in stress response. Prevents tumorigenesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Chromo domain-containing protein 1
Gene Aliases: chp1; SPAC18G6.02c
UniProt ID: (Fission yeast) Q10103
Entrez Gene ID: (Fission yeast) 2542239
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