Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
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Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Predicted reactivity: Mouse (80%), Rat (83%), Rhesus Monkey (96%).
Acts at E2F-responsive promoters as coregulator to integrate signals provided by PHD- and/or bromodomain-containing transcription factors. May act as coactivator as well as corepressor of E2F1-TFDP1 and E2F4-TFDP1 complexes on E2F consensus binding sites, which would activate or inhibit E2F-target genes expression. Modulates fat storage by down-regulating the expression of key genes involved in adipocyte lipolysis, thermogenesis and oxidative metabolism. [UniProt]
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: MGC126688; MGC126690; SERTA domain-containing protein 2; Transcriptional regulator interacting with the PHD-bromodomain 2; transcriptional regulator interacting with the PHS-bromodomain 2; TRIP-Br2
Gene Aliases: KIAA0127; Sei-2; SERTAD2; TRIP-Br2; TRIPBR2
UniProt ID: (Human) Q14140
Entrez Gene ID: (Human) 9792
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