This gene encodes an endo/exonuclease with 5'-3' exonuclease activity. The encoded enzyme catalyzes the hydrolysis of ester linkages at the 5' end of a nucleic acid chain. This enzyme is localized to the mitochondria and may play a role in programmed cell death. Alternatively spliced transcript variants have been described. A pseudogene exists on chromosome 18.
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Protein Aliases: Endo G-like 1; Endonuclease G-like 1; endonuclease G-like 2; Nuclease EXOG, mitochondrial
Gene Aliases: ENDOGL1; ENDOGL2; ENGL; ENGL-a; ENGL-b; ENGLA; ENGLB; EXOG
UniProt ID: (Human) Q9Y2C4
Entrez Gene ID: (Human) 9941