Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Peptide sequence: APKAQEIDRS NEFKNLREFW KQLGNLGVLG ITAPVQYGGS GLGYLEHVLV
Sequence homology: Cow: 86%; Dog: 79%; Guinea Pig: 86%; Horse: 79%; Human: 100%; Mouse: 79%; Rabbit: 93%; Rat: 86%
Isovaleryl-CoA dehydrogenase (IVD) is a mitochondrial matrix enzyme that catalyzes the third step in leucine catabolism. The genetic deficiency of IVD results in an accumulation of isovaleric acid, which is toxic to the central nervous system and leads to isovaleric acidemia.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Butyryl-CoA dehydrogenase; isovaleryl CoA dehydrogenase; isovaleryl Coenzyme A dehydrogenase; Isovaleryl-CoA dehydrogenase, mitochondrial; IVD
Gene Aliases: ACAD2; IVD
UniProt ID: (Human) P26440
Entrez Gene ID: (Human) 3712
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