The antibody detects endogenous levels of total GFM2 protein.
Eukaryotes contain two protein translational systems, one in the cytoplasm and one in the mitochondria. Mitochondrial translation is crucial for maintaining mitochondrial function and mutations in this system lead to a breakdown in the respiratory chain-oxidative phosphorylation system and to impaired maintenance of mitochondrial DNA. This gene encodes one of mitochondrial translation elongation factors. Its role in the regulation of normal mitochondrial function and in different disease states attributed to mitochondrial dysfunction is not known. Alternative splicing results in at least three transcript variants encoding distinct isoforms.
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Protein Aliases: EF-G2mt; EFG2; Elongation factor G 2, mitochondrial; Elongation factor G2; G elongation factor, mitochondrial 2; GFM2; hEFG2; mEF-G 2; mitochondrial elongation factor G2; mitochondrial ribosome recycling factor 2; Ribosome-releasing factor 2, mitochondrial; RRF2mt
Gene Aliases: 6530419G12Rik; A930009M04Rik; EF-G2mt; EFG2; GFM2; hEFG2; mEF-G 2; MRRF2; MST027; MSTP027; RRF2; RRF2mt