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Immunogen sequence: QGVSSLFREI TASSAVSILI KPEQETDPLP VVSRNVSADA KCKKERKKKK KVTNIISFDD EEDEQNSGDV FKKTPGAGES SEDNSDRSSV NIMSAFESPF GPNS
Highest antigen sequence identity to the following orthologs: Mouse - 75%, Rat - 76%.
SNX29 also known as RUNDC2A, is a 375 amino protein that contains one RUN domain. RUNDC2A is encoded by a gene that maps to human chromosome 16p13.13, which encodes over 900 genes and comprises nearly 3% of the human genome. The GAN gene is located on chromosome 16 and, with mutation, may lead to giant axonal neuropathy, a nervous system disorder characterized by increasing malfunction with growth. The rare disorder Rubinstein-Taybi syndrome is also associated with chromosome 16, as is Crohn's disease, which is a gastrointestinal inflammatory condition.
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Protein Aliases: RUN domain containing 2A; RUN domain-containing protein 2A; SODD; Sorting nexin-29
Gene Aliases: A-388D4.1; RUNDC2A; SNX29
UniProt ID: (Human) Q8TEQ0
Entrez Gene ID: (Human) 92017
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