This Antibody was verified by Relative expression to ensure that the antibody binds to the antigen stated. View Details
Immunogen sequence: PLGAIMPISE LQGRWATQVF KGLKTLPSQS EMMAEISKAQ EEIDKRYVES QRHTIQGDYI DTMEELADLV GVRPNLLSLA FTDPKLALHL LLGPCTPIHY RVQGPGKWDG ARKAILTTDD
Highest antigen sequence identity to the following orthologs: Mouse - 85%, Rat - 86%.
Metabolic N-oxidation of the diet-derived amino-trimethylamine (TMA) is mediated by flavin-containing monooxygenase and is subject to an inherited FMO3 polymorphism in man resulting in a small subpopulation with reduced TMA N-oxidation capacity resulting in fish odor syndrome Trimethylaminuria. Three forms of the enzyme, FMO1 found in fetal liver, FMO2 found in adult liver, and FMO3 are encoded by genes clustered in the 1q23-q25 region. Flavin-containing monooxygenases are NADPH-dependent flavoenzymes that catalyzes the oxidation of soft nucleophilic heteroatom centers in drugs, pesticides, and xenobiotics. Alternative splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Dimethylaniline monooxygenase [N-oxide-forming] 5; Dimethylaniline oxidase 5; FMO 5; Hepatic flavin-containing monooxygenase 5
Gene Aliases: FMO5
UniProt ID: (Human) P49326
Entrez Gene ID: (Human) 2330