Immunogen sequence: MVDHLANTEI NSQRIAAVES CFGASGQPLA LPGRVLLGEG VLTKECRKKA KPRIFFLFND ILVYGSIVLN KRKYRSQHII PLEEVTLELL PETLQAKNRW MIKTAKKSFV VSAASATERQ EWISHIEE\r
Highest antigen sequence identity to the following orthologs: Mouse - 98%, Rat - 97%.
APPD (Apoptosis-inducing protein D; phafin 1) is predicted through gene annotation and contains pleckstrin homology domain. It may binds to two Zn++ ions through its FYVE zinc finger domain. Biological function of this protein has not been clearly mapped yet.
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Protein Aliases: AI037048; Apoptosis-inducing protein; apoptosis-inducing protein D; Lysosome-associated apoptosis-inducing protein containing PH and FYVE domains; PH and FYVE domain-containing protein 1; PH domain-containing family F member 1; phafin 1; Phafin-1; pleckstrin homology domain containing, family F (with FYVE domain) member 1; Pleckstrin homology domain-containing family F member 1; Zinc finger FYVE domain-containing protein 15
Gene Aliases: APPD; LAPF; PHAFIN1; PLEKHF1; ZFYVE15
UniProt ID: (Human) Q96S99
Entrez Gene ID: (Human) 79156
Molecular Function: membrane traffic protein