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Immunogen sequence: HLDERIPDRS QCTSPQPGTI TPSASGCVRE RTLPRNHCDS CHCCREDVHS THAPTLQRKS AKDCKDPYCP PSLCQVPPTE KSKSTVNFSY KTETLSKPK
Highest antigen sequence identity to the following orthologs: Mouse - 94%, Rat - 91%.
The Storkhead box protein 2 (STOX2) is the only known paralog to STOX1, a winged-helix domain containing transcription factor believed to play a role in the differentiation of stem cells. STOX2 has been suggested to be part of a molecular profile unique to stem cells, and its mRNA may be part of a transcriptional profile observed with increased inflammatory response to air pollutants. Decreased STOX2 expression levels in decidua are also correlated with preeclampsia, suggesting STOX2 may play a role in the pathophysiology of preeclampsia.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Storkhead-box protein 2
Gene Aliases: KIAA1392; STOX2
UniProt ID: (Human) Q9P2F5
Entrez Gene ID: (Human) 56977
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