Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Immunogen sequence: IMLGKQLEGI WHTSIVVHKD EFFFGSGGIS SCPPGGTLLG PPDSVVDVGS TEVTEE
Highest antigen sequence identity to the following orthologs: Mouse - 95%, Rat - 95%.
Protease which deconjugates SUMO1, SUMO2 and SUMO3 from some substrate proteins. Has isopeptidase but not SUMO-processing activity. Desumoylates ZBTB46. Collaborates with UBQLN4 in the export of ubiquitinated proteins from the nucleus to the cytoplasm (PubMed:29666234). [UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: DeSI-1; Desumoylating isopeptidase 1; desumoylating isopeptidase 2; family with sequence similarity 152, member B; Palmitoyl protein thioesterase DESI1; Polyubiquitinated substrate transporter; POST; PPPDE peptidase domain containing 2; PPPDE peptidase domain-containing protein 2; S-depalmitoylase DESI1
Gene Aliases: D15Wsu75e; DeSI-1; DESI1; DESI2; DJ347H13.4; FAM152B; PPPDE2
UniProt ID: (Human) Q6ICB0
Entrez Gene ID: (Human) 27351
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