Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
This target displays homology in the following species: Cow: 93%; Dog: 100%; Guinea Pig: 93%; Horse: 92%; Human: 100%; Mouse: 86%; Pig: 100%; Rabbit: 83%; Rat: 93%; Sheep: 93%
This gene encodes a member of the proline and acidic-rich (PAR) protein family, a subset of the bZIP transcription factors. The encoded protein forms homodimers or heterodimers with other PAR family members and binds sequence-specific promoter elements to activate transcription. Chromosomal translocations fusing portions of this gene with the E2A gene cause a subset of childhood B-lineage acute lymphoid leukemias. Alternatively spliced transcript variants have been described, but their biological validity has not been determined.
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Protein Aliases: Hepatic leukemia factor
Gene Aliases: E230015K02Rik; Hlf
UniProt ID: (Mouse) Q8BW74
Entrez Gene ID: (Mouse) 217082
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