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The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
THADA (thyroid adenoma associated), also known as GITA, is a 1,953 amino acid protein that is expressed in testis, thyroid, pancreas, stomach and small intestine. Chromosomal aberrations in the gene encoding THADA are associated with benign thyroid adenomas, suggesting a potential role for THADA in tumorigenesis. The THADA gene maps to human chromosome 2, which houses over 1,400 genes and comprises nearly 8% of the human genome. Harlequin icthyosis, a rare and morbid skin deformity, is associated with mutations in the chromosome 2-localized ABCA12 gene, while the lipid metabolic disorder sitosterolemia is associated with defects in the ABCG5 and ABCG8 genes, which also map to chromosome 2.
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Protein Aliases: death receptor-interacting protein; Gene inducing thyroid adenomas protein; Thyroid adenoma-associated protein; Thyroid adenoma-associated protein homolog; tRNA (32-2'-O)-methyltransferase regulator THADA
Gene Aliases: 6530405K19; A930021O22; ARMC13; AU019899; BC052885; GITA; KIAA1767; THADA
UniProt ID: (Human) Q6YHU6, (Mouse) A8C756
Entrez Gene ID: (Human) 63892, (Mouse) 240174
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