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This product is preservative free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%-0.1%).
This antibody has specificity for Human REA/PHB2.
PHB2 acts as a mediator of transcriptional repression by nuclear hormone receptors via recruitment of histone deacetylases. This protein functions as an estrogen receptor (ER)-selective coregulator that potentiates the inhibitory activities of antiestrogens and represses the activity of estrogens. It competes with NCOA1 for modulation of ER transcriptional activity. It is probably involved in regulating mitochondrial respiration activity and in aging.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: B-cell associated protein; B-cell receptor-associated protein BAP37; D-prohibitin; MGC117268; PHB2; Prohibitin-2; Repressor of estrogen receptor activity
Gene Aliases: BAP; Bap37; BCAP37; hBAP; p22; PHB2; PNAS-141; REA
UniProt ID: (Human) Q92978
Entrez Gene ID: (Human) 11331
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